Tuberculosis among Our Neat Cattle

Tuberculosis-resistant transgenic cattle.

Tuberculosis (TB) is a devastating disease that affects humans and many animal species. In humans, TB is mainly caused by Mycobacterium tuberculosis, whereas most cases in cattle are caused by Mycobacterium bovis. However, M. bovis can also cause, albeit rarely, human TB. In PNAS, Wu et al. (1) report the use of novel genetic tools to demonstrate that insertion of one gene into a genomic “safe ...

Neat Rings

A ring is called clean if every element is the sum of a unit and an idempotent. Throughout the last 30 years several characterizations of commutative clean rings have been given. We have compiled a thorough list, including some new equivalences, in hopes that in the future there will be a better understanding of this interesting class of rings. One of the fundamental properties of clean rings i...

Does tuberculosis threaten our ageing populations?

BACKGROUND The global population is ageing quickly and our understanding of age-related changes in the immune system suggest that the elderly will have less immunological protection from active tuberculosis (TB). DISCUSSION Ongoing global surveillance of TB notifications shows increasing age of patients with active TB. This effect of age is compounded by changes to clinical manifestations of ...

Tuberculosis in cattle in Great Britain.

Genetics of Tuberculosis in Irish Dairy Cattle

There is a lack of information on genetic parameters for tuberculosis (TB) susceptibility in dairy cattle. Mycobacterium bovis is the primary agent of tuberculosis in cattle.The objective of this study was to quantify the genetic variation present among Irish Holstein Friesian dairy cattle in their susceptibility to M. bovis infection. A total of 15,182 cow and 8,104 heifer single intradermal c...